MOTS-C

4.98 · 7,496+ reviews
Batch verifiedVerified
Tracked shippingTracked
Protected

In stock

Bundle & Save
Buy 1 Get 1 Free ends in 03:00:00
Buy 1 Get 1 Free
$69.00
$138.00
Buy 3 Get 2 Free
$207.00
$345.00
Orders placed today are expected to arrive Apr 4 – Apr 6.
Purchased
Apr 2
Processing
Apr 2 - Apr 3
Delivered
Apr 4 - Apr 6
i

Buyer Protection & Quality Assurance

International orders are fully protected with reship or refund coverage. All products follow documented lab procedures and include batch-verified COAs — no dilution, no hidden changes.

Lab Report Available for This Batch
Independently tested≥99% purity verifiedClick to view
Identity Confirmed
Purity ≥99%
Independent Lab Analysis
Sterility Tested
MOTS-c Certificate of Analysis

The first peptide discovered that’s encoded by mitochondrial DNA — not nuclear DNA. A completely different origin than every other peptide on this page.

MOTS-c is a 16-amino-acid peptide encoded by the 12S rRNA gene in mitochondrial DNA. Every other peptide you’ll find — BPC-157, semaglutide, TB-500, all of them — is encoded by nuclear DNA. MOTS-c comes from the mitochondria themselves. That’s a fundamentally different origin, and it means MOTS-c is involved in how mitochondria communicate with the rest of the cell (a process called retrograde signaling).

Published studies show MOTS-c activates AMPK (the cell’s master energy sensor), regulates glucose metabolism, and influences the folate-methionine cycle that controls how cells methylate DNA. It’s one of the few compounds that bridges mitochondrial energy production and epigenetic regulation in a single mechanism. Interest in MOTS-c has grown rapidly as the role of mitochondrial-derived peptides in aging and metabolic homeostasis becomes clearer.

Why this one matters: NAD+ fuels the mitochondria. Epithalon works on telomeres. MOTS-c is the signal that mitochondria use to talk to the rest of the cell. It’s the only commercially available mitochondrial-derived peptide — a class that barely existed in the literature ten years ago.
CAS Number
1627580-64-6
Molecular Weight
2,174.7 g/mol
Molecular Formula
C₁₀₁H₁₅₂N₂₈O₂₅S₂
Appearance
White Lyophilized Powder
What Sets MOTS-c Apart
Mitochondrial origin — encoded by mitochondrial DNA, not nuclear DNA. The only commercially available peptide from this entirely separate genome.
AMPK activation — directly activates the cell’s master energy sensor, which sits upstream of glucose metabolism and fat oxidation pathways
Bridges energy and epigenetics — regulates both mitochondrial energy production and the folate-methionine cycle that controls DNA methylation
Retrograde signaling tool — the primary research compound for studying how mitochondria communicate metabolic status back to the nucleus
Batch Documentation
Same-Day Shipping
Discreet Packaging
Research Use Only. Not for human or animal consumption, medical use, or therapeutic application.

Buyer notice & verification standard

The peptide market includes anonymous resellers, short-lived operations, and vendors operating through private Telegram channels using inconsistent, unverifiable, or recycled documentation.

Aūra was built as a long-term alternative in a category where many suppliers appear briefly and disappear just as fast.

We operate under a strict verification standard: independent batch testing, lot-specific Certificates of Analysis, and clearly defined release thresholds. Batches that fail are rejected and never shipped — so labs know exactly what they’re receiving, every time. All orders are discreetly packaged with neutral labeling and documentation to ensure smooth, consistent delivery.

Trusted by 10,000+ researchers worldwide

Real labs. Real protocols. Trusted for consistency.

Researcher photo
★★★★★

"Purity and documentation matched perfectly"

Batch number, vial presentation, and stated specifications were all consistent. This level of QC is what keeps my research on track.

J.S. — Melbourne, VIC · Verified order
Researcher photo
★★★★★

"Research-grade presentation throughout"

Packaging, labeling, and handling all reflect a supplier that takes compound integrity seriously. Not a corner cut anywhere.

M.K. — Austin, TX · Verified order
Researcher photo
★★★★★

"Cold chain and shipping were flawless"

Arrived sealed, temperature-controlled, and with full analytical documentation included. Exactly what a proper research supplier should deliver.

R.L. — Toronto, ON · Verified order
Researcher photo
★★★★★

"Batch-to-batch consistency is excellent"

Third order, same reproducible results. Purity specs and documentation have been identical across every shipment.

P.D. — Miami, FL · Verified order
Researcher photo
★★★★★

"Full traceability on every order"

HPLC and MS data were clearly presented with complete batch tracking. That kind of transparency is rare and why I reordered.

A.C. — Phoenix, AZ · Verified order
Researcher photo
★★★★★

"Lab-grade quality and labeling standards"

Compound identification, concentration, and storage instructions were all clearly marked. Professional-grade from supplier to bench.

T.N. — New York, NY · Verified order

Always quality-tested, verified with third-party COAs

At every stage, Aūra Peptides batches are screened by independent labs for identity, purity, sterility, and endotoxins. Each lot is released only after it meets strict research-grade specifications and is backed by a third-party Certificate of Analysis (COA) for full transparency.

This multi-step process helps ensure that what’s on the label is exactly what’s in the vial—so researchers can focus on data, not doubt.

Identity Test

Passed

Verifies the peptide’s sequence and structure so the correct compound is present in each vial.

Purity Test

Passed

Measures purity and concentration to confirm ≥99% purity on qualifying batches.

Sterility Test

Passed

Screens for bacteria, fungi, and other microorganisms to verify sterile handling.

Endotoxicity

Passed

Tests for lipopolysaccharides (LPS) to ensure endotoxin levels stay within research limits.

Why Choose Aūra Peptides

Every Aūra Peptides batch is built around one idea: you should know exactly what's in the vial. Batches are third-party analyzed, COA-backed, and fully traceable so you're not gambling on mystery compounds.

From controlled synthesis partners to batch-specific Certificates of Analysis (COAs), Aūra is designed for teams who want clean, consistent material and repeatable outcomes — not guesswork.

Each lot is produced with vetted synthesis partners and released only after passing third-party identity and purity testing (HPLC, MS or equivalent where appropriate). Batches that don't meet spec simply don't ship.

No mystery blends. Each vial is clearly labeled with peptide name, strength, lot ID, and form (lyophilized powder or solution). Batch COAs are available for every peptide so you can document exactly which material was used in each project.

Products are packaged, labeled, and shipped as research-only reference materials. All Aūra Peptides products are supplied strictly for laboratory research use only — not for human or animal consumption, medical treatment, or diagnostic procedures.

Lots are checked for appearance and practical handling characteristics such as solubility and stability under recommended storage conditions, so you spend less time troubleshooting reagents and more time running your work.

*Aūra Peptides products are sold strictly for laboratory research use only. Not for human or animal use, or any diagnostic or therapeutic application.*

Lab technician handling vials for analytical testing

You ask,
we answer.

Straightforward answers to key questions researchers commonly ask — verification, COAs, storage, and handling for research use only.

Each Aūra Peptides lot is evaluated using analytical methods such as HPLC and mass spectrometry (where applicable) to confirm identity and purity before release.

Yes — every peptide includes a batch-specific COA reporting identity confirmation, purity data, and analytical results for full research documentation.

Most Aūra peptides are supplied as lyophilized (freeze-dried) material in sealed vials labeled with peptide name, amount, and lot number for precise tracking.

Research-grade quality is standard — our peptides target ≥98% purity by HPLC unless otherwise noted. Exact purity values are listed on each COA.

Lyophilized peptides should be stored sealed, protected from moisture and light, and kept refrigerated or frozen according to the COA or product guidelines.

After reconstitution for research use, peptides are typically stored aliquoted under refrigerated or frozen conditions to maintain stability and minimize freeze–thaw cycles.

Shelf life varies by peptide, but unopened lyophilized vials stored under recommended conditions remain stable long-term. Refer to the COA for peptide-specific stability data.

Often Ordered With